Burkholderia mallei and Burkholderia pseudomallei as bioterrorism agents: national aspects of emergency preparedness.

نویسندگان

  • Jacob Gilad
  • Idit Harary
  • Tsvika Dushnitsky
  • David Schwartz
  • Yoram Amsalem
چکیده

• Vol 9 • July 2007 B. mallei and B. pseudomallei as Bioterrorism Agents Burkholderia mallei and Burkholderia pseudomallei are the causative organisms of glanders and melioidosis, respectively. Although now rare in western countries, both organisms have recently gained much interest because of their unique potential as bio­ terrorism agents [1]. Despite being unique organisms, B. mallei and B. pseudomallei share many similarities and may be considered together in the context of a deliberate­release event. These pathogens are less familiar to medical and labora­ tory personnel than other select bioterrorism bacterial agents such as Bacillus anthracis, Yersinia pestis and Francisella tularensis and, therefore, a review of glanders and melioidosis is crucial in order to guide emergency preparedness and response to a deliberate­release event. The aim of this paper is to review the unique characteristics of these organisms in the context of bioterrorism, with special emphasis on national aspects of preparedness in Israel.

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منابع مشابه

Clinical Features and Laboratory Diagnosis of Infection with the Potential Bioterrorism Agents Burkholderia Mallei and Burkholderia Pseudomallei

Burkholderia mallei and Burkholderia pseudomallei are the causative organisms of Glanders and Melioidosis, respectively. Although now rare in Western countries, both organisms have recently gained much interest because of their unique potential as bioterrorism agents. These organisms are less familiar to medical and laboratory personnel than other select bioterrorism bacterial agents and thus h...

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Development of a polymerase chain reaction assay for the specific identification of Burkholderia mallei and differentiation from Burkholderia pseudomallei and other closely related Burkholderiaceae.

Burkholderia mallei and Burkholderia pseudomallei, the etiologic agents responsible for glanders and melioidosis, respectively, are genetically and phenotypically similar and are category B biothreat agents. We used an in silico approach to compare the B. mallei ATCC 23344 and B. pseudomallei K96243 genomes to identify nucleotide sequences unique to B. mallei. Five distinct B. mallei DNA sequen...

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عنوان ژورنال:
  • The Israel Medical Association journal : IMAJ

دوره 9 7  شماره 

صفحات  -

تاریخ انتشار 2007